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10.1002/jms.1811 23 EgglestonW.StoppacherR.SuenK.MarraffaJ

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the D-Nle-Trp-Ile-NH(CH 2 ) 5 CONH 2 analog had intermediate inhibitory activity, and the D-Nle-Met-Ile-NH(CH 2 ) 5 CONH 2 analog showed no ability to effect on Met activation

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Quenched with 4 molar HCl, Concentrated and washed Step-1 A mixture of 2-(pyrrolidin-l-yl)acetic acid hydrochloride (1000 mg, 6.06 mmol), 4-nitrophenol (842 mg, 6.06 mmol), DCC (1500 mg, 7.27 mmol) and DMAP (39 mg, 0.30 mmol) in CH3CN (50 mL) was stirred at room temperature overnight

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