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Unlike bacteriostatic water, saline typically contains no preservative, so once a vial or bag is opened, it's intended for single use only, similar to sterile water

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Activation of PARPs in the presence of excessive or accelerated DNA lesions leads to NAD+ depletion

doi: 10.1016/0009-2797(84)90145-5 85 TadashiA.ShinjiO.TakayakiS