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Trait fatigue is a symptom associated with many diseases, such as multiple sclerosis, chronic obstructive pulmonary disease (COPD), and rheumatoid arthritis, and is a result of primary disease-related mechanisms as well as secondary mechanisms not directly caused by the disease but associated with it (Behrens et al., 2023)

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A history of previous acute exacerbations is a recognized independent risk factor for predicting future exacerbations (2,85)

The acetyl form, acetyl-L-carnitine (ALCAR), shows promise to prevent age-related mental decline and boost learning markers

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