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Engineering stimuli-activatable boolean logic prodrug nanoparticles for combination cancer immunotherapy

This procedure is based on methylene blue, first acting as a photosensitizer on preparative scale (1 mmol) in the initial singlet oxygen-mediated oxidation of 2-substituted furans and subsequently - upon dilution - acting as a redox catalyst during the formation of 5HP2Os on the AON (40 nmol scale)

[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Johnson J.M., Bivalacqua T.J., Lagoda G.A., Burnett A.L., Musicki B

SNX1 and SNX2 interact with phosphatidylinositol 3-phosphate (PI(3)P) and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P 2 ) through the PX domain, thereby directly anchoring to the membrane 27