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Not only is HIF activity modulated by the complex regulation of HIF- stability, but also by the distinct interactions and dynamics among its isoforms: HIF-1, HIF-2, and HIF-3

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Chem Res Toxicol 16:261265 Waters SB, Devesa V, Del Razo LM, Styblo M, Thomas DJ (2004) Endogenous reductants support the catalytic function of recombinant rat Cyt19, an arsenic methyltransferase