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In contrast, BafA1 only induced a minor accumulation of higher molecular weight species compared with the DMSO control, likely due to an indirect effect caused by autophagy inhibition (33, 34)

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When used correctly and consistently, prescription azelaic acid can produce meaningful improvements in acne clearance, rosacea control, and hyperpigmentation reduction often where OTC options have already been tried and fallen short

Oxidative stress Multiple preclinical findings have demonstrated that LAN exposure induces oxidative stress responses, leading to the accumulation of reactive oxygen species (ROS), DNA damage, and altered expression of oxidative stress-related genes 60,61,62

Ischemic stroke can be converted to haemorrhagic stroke due to multiple factors such as ROS and inflammation (Shao et al