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China BMC Cancer

Cytokine modulation of leukemia cell proliferation and differentiation

B.WittenbornJ

In sensitive LN18 cells, we found that xCT knockdown conferred resistance to combined STF-31 and BSO treatment compared to non-targeting control (Fig

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For instance, miR-34a has been shown to target MAT2A mRNA, leading to decreased MAT 1 subunit levels and reduced SAM synthesis in hepatocellular carcinoma cells