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Future studies should evaluate e-cig usage in months other than Ramadan, in order to compare the findings and provide a broader view of e-cig withdrawal symptoms

Gao M, Monian P, Quadri N, Ramasamy R, Jiang X

As rightly noted, the systemic inflammation index (SII) is a composite measure derived from platelet, neutrophil, and lymphocyte counts, all of which are non-specific markers that can be elevated by a wide range of acute and chronic inflammatory conditions beyond smoking, such as infections, autoimmune diseases, malignancies, and other metabolic syndromes

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