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Limit of Detection (LOD) and Limit of Quantitation (LOQ): LOD and LOQ were calculated for each analyte according to CLSI EP17 guidelines

Lactobacillus reuteri , for instance, express a selenocysteine-lyase (Lamberti et al., 2 Se) to selenophosphate synthetase, which catalyze the production of the activated selenium form useful to selenocysteine sinthetase to produce L-selenocysteinil-tRNA (Lacourciere and Stadtman, LAB ecology The contribution of LAB to the overall intestinal ecosystem has been only recently elucidated

Initially, we used fivefold cross-validation to determine the best regularization parameter lambda (from 100 values ranging from 10 3 to 10 5 ) for predicting circulating TMAO in the left-out group