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Without copper coordination, the tripeptide shows much lower potency in fibroblast-stimulating assays, which suggests the metal complex is necessary to fully engage receptors or targets

In the treatment of RA, natural products can be used to treat RA through multiple pathways by regulating the activation of Nrf2 through their advantages of targeting multiple proteins and pathways

Key ingredients, such as Astragalus saponin IV and ferulic acid, inhibit ferroptosis (Peng et al., 2021)

L-Glutathione Cellular Energy Research Cellular Energy Research reference compound Studied as a cellular energy research reference compound

Results are reported as the mean SEM

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