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Examination of the distribution of apoE among the various plasma lipoproteins has shown that apoE4 has a preference for large, triglyceride-rich VLDL particles, whereas apoE3 and apoE2 associate preferentially with the small, phospholipid-rich HDL

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Another mechanism that may lead to a reversal of the physiological auditory response is the stereocilia slant, which often occurs in genetic disorders affecting the protein composition of stereocilia

This was first demonstrated by finding that chemical inhibition of the neutrophil oxidative burst exhibited PPP and G6PD dependence ( ex vivo ( Figure 1B-1 ): phagocytosis, release of neutrophil extracellular traps (NETs), and degranulation accompanied by rapid production of large amounts of extracellular ROS