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On the basis of the increased flux in TCA cycle, AMPK facilitates FOXO1-dependent IDH2 expression, and revitalizes the enzymatic activity of IDH2 by the PGC-1/SIRT3 pathway

Reactive oxygen species, nutrition, hypoxia and diseases: problems solved

A plant triterpenoid Avicin D stimulates adipocytic differentiation of bone marrow stromal cells and promotes their pro-survival effects on acute monoblastic leukemia cells

Its natural occurrence in the body also means established metabolic pathways for processing and elimination

Ovarian tumors with high levels of inflammatory gene expression have poor response to immunotherapy, decreased cytotoxic T cell activity, and enhanced M2 macrophage infiltration, according to transcriptomic studies [167]

Masarova L, Cortes JE, Patel KP, O'Brien SM, Nogueras Gonzlez GM, Konopleva M, Verstovsek S, Garcia-Manero G, Ferrajoli A, Kadia TM, Ravandi F, Borthakur G , Dellasala SE, Jabbour EJ, Kantarjian HM