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Glutathione S -transferases in kidney and urinary bladder tumors

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Migliore and Copped, 2009[82])

Hydroxocobalamin is the standard UK preparation, administered intramuscularly for conditions like pernicious anaemia and gastrointestinal malabsorption B12 acts as a cofactor in DNA synthesis, red blood cell formation, and nervous system function, supporting energy metabolism pathways Common side effects include injection site reactions, mild gastrointestinal upset, and temporary urine discolouration, with serious reactions being rare NHS access requires GP assessment with blood tests

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It is especially critical for the DNA synthesis of oligodendrocytes, the cells that produce myelin, as well as the synthesis of myelin itself 1