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These results provide important proof-of-concept for treating OA by inhibiting ferroptosis (Wang X

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[Abstract]2025 Sep 30;388(Pt 1):114283

- Incorporate into serums for daily skincare routines - Add to creams and lotions for enhanced formulation profiles - Formulate in sheet masks or leave-on treatments - Blend with other antioxidants in multi-functional products - Use in rinse-off products such as cleansers and washes - Combine with hydrating agents for balanced formulations 1

On the other hand, the presence of the GIY-YIG domain reduces the ability of GRXS16 to suppress the susceptibility of yeast grx5 mutant to oxidative stress