enzymatic activity assay for glutathione s-transferase Simple method visual detection of and inhibition using cysteamine-capped gold nanoparticles as colorimetric probes | Discover Metals The reactions catalysed by GST:

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DOI: 10.3390/ijms13078308 20

Neurological Damage: Prolonged vitamin B12 deficiency, especially if left untreated, can lead to irreversible neurological damage, including demyelination of nerve fibers in the brain and irreversible neurological deficits

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A compromised glutathione system in the brain has a strong correlation with oxidative stress and has been shown to be implicated in neurodegenerative diseases such as Alzheimers disease, Parkinsons disease, amyotrophic lateral sclerosis, progressive supranuclear palsy, Huntingtons disease and multiple sclerosis [3-5]