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Succinylcholine's Risk for Hyperkalemia & Rhabdomyolysis in Muscular Dystrophy In patients with primary skeletal muscle myopathies, most notably Duchenne's or Becker's muscular dystrophy, hyperkalemia occurs via a different, catastrophic cellular pathway: Muscle Membrane Fragility : The underlying genetic defect in muscular dystrophy alters the structural integrity of the skeletal muscle cells, rendering the surface cell membrane (sarcolemma) exceptionally fragile and highly vulnerable to physical stress (Sandoz Inc, 2010

Research shows that it also plays a key role in improving insulin resistance in the body

Oxford Medical Case Reports

Normally, a persons extracellular (outside the cells/in the blood) potassium concentration falls between 3.5 to 5 mmol/L

10.1016/j.lfs.2022.120870 11 BaiR.GuoJ.YeX

J Neurosci