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It restores normal cellular communication and reduces fibrosis while promoting healthy tissue remodeling

Aishajiang R, Liu Z, Wang T, Zhou L, Yu D

This ensures that the therapy is aligned with personal health goals and monitored for safety and effectiveness over time

An illustrative example of this is observed in the impact of the ECM on T cells, whose ability to perceive and react to environmental stiffness underscores their mechanosensitivity (72)

ClinicalTrials.gov lists 3 ongoing or completed trials (accessed February 12, 2026): NCT05239615 (topical for photoaging, Phase II, completed 2024, no results posted) [12]

If yes, your skin may simply need longer adjustment