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Associated with a lower risk of cardiovascular diseases, including stroke and heart disease

Although the mechanisms whereby TNBS cause an inflammatory response are not completely defined, this response is thought to be initiated by macrophage-mediated recognition and degradation of the TNBS-modified cells and proteins within the colonic interstitium (Grisham et al, 1991

Ethics statement Buffy coats were obtained from healthy human donors from the State Hospital (Copenhagen, Denmark), following informed, written consent in accordance with legislation and guidelines from the local ethics committee (Region Hovedstaden, Denmark)

[DOI] [PubMed] [Google Scholar] 92.Watanabe T., Arai Y., Mitsui Y., Kusaura T., Okawa W., Kajihara Y., Saito I

However, the precise mechanisms driving IL-6 upregulation during ischemia remain incompletely understood

H., Salvi, R