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Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics

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At a time when many of the standard drugs used to treat such diseases are frequently ineffective, these new targeting directives provide a timely opportunity

(2019) found that inhibiting canonical Wnt signal transduction in bone marrow stromal cells prevented the development of MDS and proposed that activation of -catenin signalling in the bone marrow of MDS patients may be a new treatment strategy that reduces -catenin levels or inhibits Wnt/-catenin signalling

Jan 21 2021;13(2)doi:10.3390/nu13020302