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We recognized there are several advantages to choosing a non-invasive stool-based CRC screening test as a first step compared to a screening colonoscopy, including relative ease of administering the test and potentially reducing the experience of unnecessary burdensome preparation and invasive procedures

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Minimally Invasive Procedures : Aspiration : If the nodule is fluid-filled or an abscess has formed, aspiration with a fine needle can help to drain the contents and reduce the size of the nodule

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This secondary enhancement of the inflammatory response can derive from short-term changes to innate cells like macrophages through a phenomenon called trained immunity 9 , and/or from activation of memory T cells and B cells generated from the initial injection