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Many other molecules that participate in autophagy routing are selective receptors (SAR) for cargos to be degraded by lysosomal enzymes (Conway et al., 2020)

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Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers

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A.AshafaqM.Abdur RubR.et al (2018)

As a proof of concept, disruption of the regulatory loop linking p53, the cell cycle, and clock genes has been correlated to cancer in mouse models 38