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However, the buffering capacity becomes limited as impairment of SAT expansion causes IR [22, 23, 24] as the excess fat are deposited in the visceral adipose tissue (VAT) as well as ectopically in the skeletal muscle, liver, kidney, and heart tissues [25]

Every drop of sweat contains essential electrolytes and nutrients that help your muscles, nerves, heart, and cells function properly

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Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells

Traditional obesity intervention strategies (e.g., dietary control, exercise, conventional weightloss drugs) are often limited by slow onset, obvious side effects, and high rebound rates, and can hardly fundamentally reverse the abnormal metabolic phenotype of adipose tissue