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All searched spectra were imported into Scaffold (v5.3, Proteome Software) and scoring thresholds were set to achieve a peptide false discovery rate of 1% using the PeptideProphet algorithm

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469 The mitochondrial protein sideroflexin 1 (SFXN1) is responsible for importing iron from the cytoplasm to the mitochondria, and SFXN1 deficiency leads to mitochondrial respiratory chain damage, affecting the biogenesis and assembly of complex III

FIGURE 2 Worthy of mention is that nuclear receptor coactivator 4 (NCOA4) can promote iron storage or release from ferritin and plays a crucial function in maintaining a dynamic balance of intracellular iron

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Dietary folate intake or folate plasma concentration was negatively correlated to homocysteine level, not only in diseased (Mansoor et al, 1995