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doi: 10.1111/j.1460-9568.2006.05036.x

10.1074/jbc.M506096200 46

The glutathione precursor N-acetylcysteine improves immune function in postmenopausal women

Although it is hard to ascertain the cause of pyroglutamic acidosis because most of the reported patients had multiple medical comorbidities and/or kidney dysfunction or kidney failure, all of the patients were using APAP

Long-term use has been associated (in some reports) with lower zinc levels

If the safety and modest efficacy data from the published trials translate to our patient population, it would give us a tool that acts directly on fat cell metabolism rather than appetite, with a side effect profile that appears extremely well-tolerated