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When this regulatory mechanism is impaired, SQOR accumulates abnormally, leading to a sharp decrease in testicular H 2 S and severe oxidative stress (elevated ROS levels and diminished antioxidants like glutathione and SOD)

Bning Journal: Molecular therapy : the journal of the American Society of Gene Therapy Journal ranking: Q1 Key takeaways: Tropism-modified AAV vectors with novel receptors significantly improve cutaneous gene therapy by increasing cell entry efficiency and targeting v8 integrin, overcoming safety concerns.

Metabolic control through the PGC-1 family of transcription coactivators