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Lipid digestion and absorption is more complicated than carbohydrate and protein digestion and absorption because of lipid solubility characteristics, and involves emulsification of lipids by bile salts, hydrolysis by pancreatic lipase and colipase, solubilization of fatty acids and monoglycerides into mixed micelles, absorption, reesterification, chylomicron formation, and transport into the intestinal lymphatics or portal capillaries

Personal or family history of medullary thyroid cancer or multiple endocrine neoplasia (MEN) type 2 Please note that these eligibility criteria are not exhaustive, and it is crucial to consult with your healthcare provider for a comprehensive assessment of your individual circumstances

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10.1016/J.FERTNSTERT.2021.03.039 6 BeltrnC.TrevioC

While efficacy endpoints for weight loss in those trials were modest, the compound exhibited a favorable safety profile, supporting its later GRAS designation for food use