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doi: 10.1038/s41418-020-00685-9 45 OuMJiangYJiYZhouQDuZZhuHet al

Due to the short-term exposure to NAs (24 h) in the present study, the in vitro alkaline comet assay likely detected mainly DNA N -alkylation damage and its subsequent repair by base excision repair (BER)

Longevity pathways activated NAD+-dependent enzymes like SIRT1, tied to DNA repair and stress response, become more active

Immunopharmacology 48 , 173183 (2000)

According to ProHealth's FAQ, BPC-157 is generally well-tolerated and no significant adverse effects have been reported in the human studies that exist.* The preclinical literature similarly reports no significant toxicities in animal models

Importantly, iron deposition also correlates with quantitative memory decline