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Pistone G, Marino A, Leotta C, Dell'Arte S, Finocchiaro G, Malaguarnera M

Schirinzi et al., 2020

10.1113/jphysiol.2007.148338 Summary Keywords mdx, skeletal muscle contraction, NAC, oxidative stress, fiber branching, muscle damage, dystrophy, split fiber Citation Redwan A, Kiriaev L, Kueh S, Morley JW, Houweling P, Perry BD and Head SI (2023) Six weeks of N-acetylcysteine antioxidant in drinking water decreases pathological fiber branching in MDX mouse dystrophic fast-twitch skeletal muscle

Relevance of the project to Immunology (examining immune mechanisms or having only an immunology component)

The biomass concentration, intracellular glutathione content, and volumetric glutathione production of GCI/ SHM2 , GCI/ CYS4 , and GCI/ SHM2 / CYS4 at 48 h were apparently higher than those of the GCI/Vector (Fig

They acknowledge GHK-Cus known benefits on collagen and inflammation, but they also stress that injectable applications lack strong clinical trial data