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Although the C-terminal SAM-binding site is located away from the catalytic center, it was revealed that SAM binding induces a structural rearrangement of the catalytic core that relieves autoinhibition and stabilizes an activated conformation ( Historically, aminooxyacetic acid (AOAA) has been the most commonly used inhibitor of CBS (Whiteman et al., 2011

Being a part of traditional medicines, black cumin and essential oil (NSO) have great potentials as anti-diabetic agents (Table 4)

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Once PUFA-containing phospholipids become integrated into cell membranes, they are highly susceptible to peroxidation