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In addition, cholesterol accumulation in MIM interferes with the assembly of respiratory supercomplexes, underlying the impairment in the respiratory capacity, stimulates the generation of superoxide anion resulting in oxidative stress, and stabilizes hypoxia inducible factor-1 (HIF-1), leading to metabolic reprogramming with impaired oxidative phosphorylation and stimulated glycolysis [136]

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Experimental and therapeutic medicine,2021,21(2) About Angel Yeast Extract-Savoury: Angel YE (yeast extract) made from edible yeast, by degradation the protein and nucleic acid in the yeast cells into nutritional seasonings with the application of modern biotechnology, has the advantages of increasing the fresh flavor, reducing salt, balancing the odor, strong tolerance and food properties, which promotes the global healthy operation of salt reduction and "clean label "

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Accessed 1/13/2015