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Mecklenburg confirmed the correlation between serum ferritin and serum hepcidin in the case of inflammation (Mecklenburg et al., 2014)

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Together, these studies argue that FSP1 can represent (1) a context-dependent essentiality (for example, metastatic niches) and/or (2) a stand-alone oxidative defense node that becomes rate limiting for tumor survival under physiological stressors encountered in vivo