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PMID 35658024

The key context for this comparison is that both compounds are strictly preclinical -- all claims about cognitive effects are based on animal models, and the translation of these findings to human cognition is uncertain

Researchers reported induction of hTERT expression, restored telomerase enzymatic activity, and telomere elongation

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Baltimore, MD: Williams & Wilkins

A common mouse model, the APP/PS1 mouse, expresses the Swedish mutation of APP together with the E9 truncated mutation of PS1 [16], resulting in cognitive impairment despite reduced -secretase activity [17]