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The physiological effects of nitric oxide are mediated by the soluble guanylyl cyclase (sGC) receptor, which generates guanosine 3',5'-cyclic monophosphate (cyclic GMP or cGMP), the second messenger of signaling systems

Available at: Accessed 9/23/18

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Oxidative stress in traumatic brain injury

The next step involves the enzyme glutathione synthetase, responsible for adding glycine to the dipeptide to produce GSH (-glutamylcysteinylglycine) and also requires coupled ATP hydrolysis (Meister, 1974)