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Potential therapeutic strategies for targeting cuproptosis in cancer In recent decades, a growing body of evidence suggests that the Cu-complex might serve as a potential therapeutic target for treating cancer, as Cu has been shown to promote the death of cancer cells via apoptosis and/or an accumulation of free radicals

The anti-oxidants like Glutathione will protect against oxidative damage

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Glutathione also participates in maintaining the redox state of protein thiol groups (sulfhydryl groups), which can influence protein structure, enzyme activity, and cellular signaling behavior under stress

Reality: Low-grade dehydration (versus acute and clinical dehydration) is a chronic, widespread problem that has major impacts on well-being, energy, appearance and resiliency

10.1016/S0022-5193(03)00218-2 140 WuH.LinL.GiblinF.HoY