glutathione paracetamol poisoning Target biomarker profile for the clinical management of overdose - Vliegenthart - 2015 - British Journal of Clinical Pharmacology Too much paracetamol = dangerous

Too much paracetamol = dangerous because of how your liver processes it. *Normal dose:* About 90 95% gets broken down safely by glucuronidation + sulfation non toxic stuff you pee out. *The problem Acetaminophen Toxicity: OPPOSITE EFFECTS OF TWO FORMS OF GLUTATHIONE PEROXIDASE ScienceDirect Good ol' paracetamol: 'But an overconsumption takes its toll' Journal of Anaesthesia Practice A spatial temporal model for zonal hepatotoxicity of acetaminophen ScienceDirect Mechanism of paracetamol toxicity NUS Faculty of Science NUS Faculty of Science paracetamol overdose glutathione depletion Toxicology of Poisoning Pharm.D Aid The multiple mechanisms and modes

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