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Description

Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria

Nat Commun 2019;10:3126

F., Jones, A., Alewood, D

Individuals with aldehyde dehydrogenase 2 (ALDH2) deficiency, most prevalent in East Asian populations, accumulate acetaldehyde during alcohol metabolism, producing severe flushing, tachycardia, and nausea even at low intake levels