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Conclusion: The high prevalence of obesity and metabolic comorbidities in the Hispanic population of the Rio Grande Valley significantly contributes to liver disease severity the more metabolic syndrome criteria a patient has, the more likely they are to have moderate-to-advanced fibrosis, with diabetes and hypertension being most associated

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Studies have unveiled that glycation of TTR may contribute to cellular stress and toxicity in FAP patients by activating NF-B ( Advanced glycation end-products disrupt blood brain barrier A unique set of blood vessels that are involved in vascularizing the CNS, forms a crucial part of blood brain barrier (BBB