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Hyperglycaemia progressively impairs these transporters, accelerating beta-cell apoptosis and microvascular complications

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J Vet Intern Med 2010;24:1350-1357

Most people notice appetite changes within the first two weeks and measurable weight loss within the first month

J., Lee W

However, it remains unclear whether hepatic steatosis per se in MAFLD contributes to an elevated risk of mortality in individuals with overweight/obesity, metabolic dysregulation, or type 2 diabetes mellitus (DM) (referred to as the metabolic dysfunction-association (MA) group), which are known significant risk factors for increased mortality