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Treatment with FOXO4-DRI at 25 M in serum-limited senescent fibroblast and keloid organ culture models promoted apoptosis, decreased G0/G1 phase cells, and induced p53-pS15 nuclear exclusion confirmed by Annexin V-FITC/PI apoptosis assays and TUNEL staining of keloid organ cultures at days 3, 7, and 10

Safety & Medical Supervision GHK-Cu therapy is generally well tolerated but must be used responsibly

Exogenous human growth hormone reduces body fat in obese women

Senescent cancer cell vaccines induce cytotoxic T cell responses targeting primary tumors and disseminated tumor cells

2007 Apr;48(4):1724-34

Ross AP, Nicholas J, Tai MH, et al