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Matrix Remodelling Investigations: Exploring extracellular structure behaviour and cellular microenvironments

Driven by localized iron overload and the continuous generation of reactive oxygen species, the resulting metabolic dysfunction renders vulnerable tissues highly susceptible to ferroptosis

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Methods Patients and study design The study protocol was conducted in accordance with the guidelines contained within the Declaration of Helsinki and was approved by the ethics committees of Yokohama City University and Kyoto Prefectural University of Medicine

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