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Subsequent activation signals, including ROS, K + efflux, and mitochondrial DNA (mtDNA) release, initiate the formation of the NLRP3 inflammasome

So, people with MTHFR mutations may have folate or vitamin B9 deficiency

But then there were more

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Chellasamy G, Arumugasamy SK, Govindaraju S, Yun K (2022) Green synthesized carbon quantum dots from maple tree leaves for biosensing of cesium and electrocatalytic oxidation of glycerol