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The all-D-amino acid composition provides resistance to proteolytic degradation while maintaining binding specificity for p53

A statistically significant increase in cancer was observed in rats receiving semaglutide at all dose levels (greater than 2X human exposure)

The albumin-binding domain as a scaffold for protein engineering

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The determination of early apoptosis was done at 24 h by aspirating the MM cells away from the BMSC and using Annexin V assay with flow cytometry and cytotoxicity at 96 h using DIMSCAN assay as previously described

This was a very small study, however, and lacked a blinded placebo group