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Obesity Pharmacotherapy: Current Perspectives and Future Directions, Misra M., Journal (Current Cardiology Reviews, Volume 9, Issue 1, February 2013, Pages 3354)

This results in an increased inflammatory response, which damages tissue cells, such as vascular ECs and pancreatic -cells, ultimately leading to Mets

Discussion This review covers the importance of maintaining NAD + levels for cellular homeostasis and mitochondrial maintenance, as well as evaluating established and novel NAD + boosting strategies from simple supplementation of precursors to modulation of enzymes by drugs