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The amine and carboxylic acid groups of carnitine are the key groups for OCTN2 to recognize it, and the hydroxyl group of carnitine is esterified by acyl derivatives and does not hinder the recognition effect of OCTN2, indicating that OCTN2 has high substrate diversity and adaptability and is able to process a variety of acylcarnitines [162]

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Associations of dietary diversity with the gut microbiome, fecal metabolites, and host metabolism: results from 2 prospective Chinese cohorts

Key takeaways: Carnitine is necessary for transporting long-chain fatty acids into mitochondria for energy production, which is particularly important in skeletal muscles and heart function