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While the exact etiology of AD remains unclear, its development is linked to a range of factors, including genetic predisposition, abnormal protein aggregation, neurotransmitter imbalance and neuronal damage (46)

Nucleic Acids Res 45:25462557 Hanzlikova H, Kalasova I, Demin AA, Pennicott LE, Cihlarova Z, Caldecott KW (2018) The importance of poly(ADP-ribose) polymerase as a sensor of unligated Okazaki fragments during DNA replication

Under conditions of metabolic stress, it migrates to the cell nucleus, where it activates a suite of genes governed by AMPK (AMP-activated protein kinase), the master cellular energy sensor

Concurrent ingestion of paracetamol and iron resulted in increased rate of iron absorption and decreased extent of drug absorption

Initially, 450 L of water with 150 L of chloroform were added, vortexed and centrifuged at 20,000 g for 10 min

The NF-B inhibitors attenuate hepatic injury in bile duct ligated rats