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Neurology 69 , 835841 (2007)

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However, the top two ranked administration routes were the oral route (78.3) and the IM route (49.6)

Safety Profile Across all six human trials and the extensive preclinical work, the safety picture is quite clean: No serious adverse events attributed to the compound No effect on IGF-1 No impairment of glucose tolerance or insulin sensitivity No genotoxic activity Most common side effects: mild injection site irritation, occasional headache or fatigue all transient This is genuinely one of the better-characterized peptides from a safety standpoint, largely because it actually went through a formal development process with proper clinical oversight

While AHK-Cu likely shares some of GHK-Cu broader properties, given the structural similarity, the documented evidence emphasizes scalp and hair applications