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DNA methylation and demethylation in mammals

Avoid use with direct acids, retinoids, and strong antioxidants

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10.1016/j.fct.2018.12.002 52 KimD

The transition state searches were carried out using B3LYP/6-31 G** for C79, C26, and C83 and B3LYP/6-31 G* + for C23 and C8, as this protocol reliably locates transition states (verified by a single imaginary frequency obtained for each transition state see Supplementary Table 9)

Establishing consensus on core outcome sets, minimum reporting standards, and shared dosing frameworks would substantially strengthen the evidence base, reduce heterogeneity and enable future meta-analyses