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In the early phase of tumor development, these cells prefer glycolysis over oxidative phosphorylation because glycolysis can supply ATP faster to rapidly proliferating cells as compared to oxidative phosphorylation and also reduces the oxidative stress on tumor cells (Pfeiffer et al., 2001)

J Biol Inorg Chem 19(8):128793

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To further assess combined age-sex effects, differences in TMAO log AUC (placebo minus pomegranate) were calculated per participant and analyzed using linear models including age group, sex, and their interaction

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10.1080/15548627.2018.1491489 Autophagy 146 ItanoY.NomuraY