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Description

MTHFR is a gene that helps your body convert folate and B12 into forms it can use

While many small molecules have been developed to target RNA structures 1 , most studies have focused on interactions with reference genomes, overlooking the potential influence of genetic variation

Naive PSCs tend to have a high [-KG]/[succinate] ratio because active PDH and FAO supply -KG (through enhanced TCA flux), whereas succinate is efficiently oxidized via SDH