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Considering the data for the whole set of PCOS patients, the AUC HIE decreased after 12 weeks but the reduction was significant only after 24 weeks of integrative treatment (Fig

In a multiple stepwise logistic regression model including type 2 diabetes (T2D), obesity, arterial hypertension, dyslipidemia, male sex and SLF by FIB-4, both SLF and T2D were significantly associated with diastolic dysfunction (Figure 1)

Open Heart 5 , e000784 (2018)

Further studies demonstrated that BHB induced -hydroxybutyrylation of histone H3 at lysine 9 (H3K9bhb) and upregulated matrix metalloproteinase-2 (MMP-2) expression [10]